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  • Significant and increasing depressive symptoms are associated with increased risk of new cardiac events in people with a heart attack in the previous year

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Prognosis
Significant and increasing depressive symptoms are associated with increased risk of new cardiac events in people with a heart attack in the previous year
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http://dx.doi.org/10.1136/ebmh.10.2.42

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    Kaptein KI, de Jonge P, van den Brink RHS, et al. Course of depressive symptoms after myocardial infarction and cardiac prognosis: a latent class analysis. Psychosom Med 2006;68:662–8.OpenUrlAbstract/FREE Full Text

    Q Do depressive symptoms predict the risk of new cardiac events in people with a recent heart attack?

    METHODS

    Embedded ImageDesign:

    Prospective cohort study.

    Embedded ImageSetting:

    Four hospitals, the Netherlands. Recruitment: September 1997 to September 2000.

    Embedded ImagePopulation:

    528 people (81% male; mean age 61 years) with clinically diagnosed myocardial infarction (chest pain for ⩾20 min, creatinine phosphokinase MB levels ⩾10% or creatinine phosphokinase 100% above normal, and new pathological Q waves on ECG in ⩾2 leads). Exclusions: poor physical condition; life expectancy ⩽1 year due to another condition; non-Dutch speaking; cognitive dysfunction; heart attack occurred after admittance for another condition; or follow-up planned in a hospital not involved in the study.

    Embedded ImagePrognostic factors:

    Depression assessed at baseline (in hospital), 3, …

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    Footnotes

    • For correspondence: Peter de Jonge, PhD, Oostersingel 59, Box 30001, Groningen 9700RB, the Netherlands; p.de.jonge{at}med.umcg.nl

    • Source of funding: Netherlands Organisation for Scientific Research, the Netherlands.

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    Copyright information:

    Copyright 2007 by the Evidence-Based Mental Health

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    • Et al
      Et al
      BMJ Publishing Group Ltd, Royal College of Psychiatrists and British Psychological Society
      Evidence-Based Mental Health 2007; 10 39-40 Published Online First: 25 Apr 2007. doi: 10.1136/ebmh.10.2.39