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The articles we select for Evidence-Based Mental Health must pass two stages: first they must pass our basic validity criteria and then the editors assess each article for clinical relevance. A number of articles meet the inclusion criteria but are not abstracted due to lack of space. We will highlight the most interesting of these here and list the rest.
Do physicians screen for depression and treat it in patients who suffer a heart attack? It seems unlikely although the evidence suggests they should. Following a myocardial infarction, depression is as good a predictor of mortality as smoking, obesity, or indeed heart failure and an abundance of observational studies have explored the relation between psychological morbidity and coronary heart disease. In this issue of EBMH two such studies have been abstracted (page 42 and page 43) and two more are listed below ( OpenUrlCrossRefPubMedWeb of Science) ( OpenUrlCrossRefPubMedWeb of Science) . The safety and effectiveness of selective serotonin reuptake inhibitors in depressed patients with comorbid heart disease has also been demonstrated in a series of clinical trials: SADHART,1 ENRICHD,2 and CREATE.3 Given this body of evidence, the obvious question is whether the treatment of depression in these patients will reduce the likelihood of a future cardiac event?
Much to the outrage of assorted newspaper columnists in the UK, the …
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