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Intermittent explosive disorder is common, has an early age of onset and is associated with the development of other mental disorders in the US population

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Q How common is intermittent explosive disorder in the US population?


Embedded ImageDesign:

Cross sectional study.

Embedded ImageSetting:

General population, US; recruitment February 2001 to April 2003.

Embedded ImagePopulation:

9282 people taking part in the National Comorbidity Survey Replication. Exclusions: <18 years old; or diagnosis of bipolar disorder.

Embedded ImageAssessment:

A fully structured diagnostic interview was carried out to assess participants for anxiety disorders, mood disorders, substance disorders, oppositional defiant disorder, conduct disorder, attention deficit/hyperactivity disorder and intermittent explosive disorder (IED). Lifetime IED was defined as three or more anger attacks that resulted in serious assault or destruction of property. Twelve-month prevalence was defined as three lifetime attacks and at least one attack in the last month. …

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  • For correspondence: Ronald C Kessler, PhD, Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA; kessler{at}

  • Sources of funding: National Institute of Mental Health, National Institute on Drug Abuse, Substance Abuse and Mental Health Services Administration, Robert Wood Johnson Foundation and John W Alden Trust, USA.

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