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Methylphenidate improved symptoms in children and adolescents with conduct disorder independent of ADHD severity

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Question Can methylphenidate improve symptoms in children with conduct disorder with and without attention deficit hyperactivity disorder (ADHD)?


Randomised, double blind, placebo controlled trial with 5 weeks follow up.


Schools in New York State, USA.


84 children between 6 and 15 years of age (mean age 10 y, 89% boys) referred from schools and juvenile probation officers who had a modified DSM-III diagnosis of conduct disorder (lying could not qualify for diagnosis) and who were attending school. Children with substance disorders were excluded. 69% of children had comorbid ADHD. 74 children (88%) completed the study (37 in each group).


41 children were allocated to methylphenidate, preset titration, …

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