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Cognitive behaviour therapy improved functional impairment and fatigue in patients with chronic fatigue syndrome

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Objective

To compare cognitive behaviour therapy (CBT) with relaxation techniques for patients with chronic fatigue syndrome (CFS).

Design

Randomised controlled trial with 6 month follow up.

Setting

A hospital clinic in London, England.

Patients

60 patients (mean age 35 y, 68% women) with CFS. Patients taking antidepressants or anxiolytics were included if the dose was stable for 3 months before and during the trial; 53 patients (88%) completed the study. Exclusion criteria were somatisation disorder, severe depression, ongoing physical investigations, concurrent new treatment, or inability to attend all sessions.

Intervention

Patients were allocated to CBT (n=30) …

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