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To compare cognitive behaviour therapy (CBT) with relaxation techniques for patients with chronic fatigue syndrome (CFS).
Randomised controlled trial with 6 month follow up.
A hospital clinic in London, England.
60 patients (mean age 35 y, 68% women) with CFS. Patients taking antidepressants or anxiolytics were included if the dose was stable for 3 months before and during the trial; 53 patients (88%) completed the study. Exclusion criteria were somatisation disorder, severe depression, ongoing physical investigations, concurrent new treatment, or inability to attend all sessions.
Patients were allocated to CBT (n=30) …
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