Quetiapine v some classical antipsychotics in patients with schizophrenia*

Weighted event rates
OutcomeQuetiapineAntipsychotics (hal, clpz)RRR (95% CI)NNT (CI)
Leaving the study early due to adverse effects† 7%17% 75% (46 to 88)11 (6 to 42)
Dystonia‡ 1% 5% 85% (21 to 97)29 (13 to 111)
QuetiapineAntipsychotics (hal, clpz)RRI (CI)NNH (CI)
*Hal = haloperidol; Clpz = chlorpromazine. Other abbreviations defined in glossary. RRR, RRI, NNT, NNH, and CI calculated from data in article. †Random effects model (statistical heterogeneity). ‡Fixed effects model.
Dry mouth‡10% 3%185% (46 to 457)16 (10 to 38)
Sleepiness‡16%11% 51% (5 to 116)21 (11 to 188)