Responder rates for St John's wort (SJ) v control in depressive disorders†

Weighted event rates
Comparison at a mean follow up of 5.1 weeksSJControlRBI (95% CI)NNT (CI
SJ v placebo‡56%25%140% (70 to 239)4 (3 to 6)
Comparison at a mean follow up of 5.6 weeksRBR (CI)NNH
†NS=not significant; RBR=relative benefit reduction. Other abbreviations defined in glossary; RBI, RBR, NNT, NNH, and CI calculated from data in article.
‡Heterogeneity existed among trials.
SJ v antidepressants51%52%3% (−12 to 16)NS