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ABSTRACT FROM: Cooper DC, Trivedi RB, Nelson KM, et al. Antidepressant adherence and risk of coronary artery disease hospitalizations in older and younger adults with depression. J Am Geriatr Soc 2014;62:1238–45.
What is already known on this topic
Depression is a public health threat, particularly due to its bidirectional, adverse associations with common chronic conditions including coronary artery disease (CAD). The American Heart Association recognises depression among the major risk factors for morbidity and mortality following an acute coronary event.1 Depression in older adults is associated with greater risk of potentially preventable medical hospitalisations—such as those for angina—and early rehospitalisation after myocardial infarction.2 Yet, little is known about whether depression treatment could mitigate cardiovascular risk or associated service use.
The study was conducted in the Veterans’ Affairs health system, the largest integrated healthcare system in the USA. The sample consisted of 40 844 adults under 65 years and …
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