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Question: Is cognitive behavioural therapy (CBT) effective for the treatment of childhood and adolescent anxiety disorders?
Outcomes: Primary outcomes Remission of the anxiety disorder, as diagnosed by valid structured interviews for the Diagnostic and Statistical Manual (DSM) or the International Classification of Diseases (ICD) child and adolescent anxiety disorders (Anxiety Disorder Interview Schedule for Parents or Children (ADIS-P and ADIS-C), Diagnostic Interview Schedule for Children, Adolescents and Parents or Clinical Global Impression scale (CGI-I)); and acceptability of treatment as determined by dropout.
Design: Systematic review and meta-analysis.
Data sources: The Cochrane Depression, Anxiety and Neurosis Group Register (CCDANCTR), searched July 2012. This contains trials from the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, MEDLINE and PsycINFO from the respective database inception to most recent search date of CCDANCTR (May 2012), supplemented by data from international trial registers, drug companies and handsearch of key journals, conference proceedings and other non-Cochrane systematic reviews and meta-analyses.
Study selection and analysis: RCTs (including cluster and crossover RCTs) were eligible if they examined the use of CBT (at least nine sessions) in children or adolescents (age 4–18 years) with DSM or ICD diagnosis of generalised …
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