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Retrospective cohort study.
Follow up period:
6 months following initial antidepressant prescription.
Members of a prepaid health plan in Washington and Idaho, USA.
65 203 people starting a new episode of antidepressant treatment between January 1992 and June 2003.
Treatment with a newer antidepressant (bupropion, citalopram, fluoxetine, fluvoxamine, mirtazapine, nefazodone, paroxetine, sertraline, escitalopram, venlafaxine) or older antidepressant (primarily tricyclic antidepressants (76%) and trazodone (21%)).
Suicide attempt requiring hospitalisation (verified through hospital discharge records) or death by suicide (verified through death certificate).
The newer antidepressants did not increase risk of suicide attempt or suicide death …
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