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First episode psychosis: olanzapine and haloperidol provide similar improvements in quality of life and social functioning

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Q Is olanzapine more effective than haloperidol in improving quality of life and social functioning in people with first episode psychosis?

METHODS

Embedded ImageDesign:

Multicentre randomised controlled trial.

Embedded ImageAllocation:

Unclear.

Embedded ImageBlinding:

Double blind.

Embedded ImageFollow up period:

One year.

Embedded ImageSetting:

Fourteen medical centres in North America and Western Europe; time period not reported.

Embedded ImagePatients:

263 people aged 16–40 years with first episode schizophrenic spectrum psychosis (DSM-IV) and active psychotic symptoms. Participants had to have less than five years of symptoms with any recovery period lasting less than six months, and antipsychotic …

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