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Poor social and interpersonal functioning prior to diagnosis predicts poor outcome for people with first episode psychosis

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 Q Does poor social, interpersonal, school, and work functioning before diagnosis predict outcome for people with a first episode of psychosis?

METHODS

Embedded ImageDesign:

Prospective cohort study.

Embedded ImageSetting:

Calgary Early Psychosis Program, Calgary, Canada.

Embedded ImagePopulation:

194 people with first episode psychosis (DSM-IV; mean age 24 years; 30% women. Exclusions: non-English speaking.)

Embedded ImagePrognostic factors:

Functioning prior to psychosis was assessed using the Premorbid Assessment Scale (PAS). Positive and negative symptoms of psychosis (Positive and Negative Syndrome Scale), social functioning (Quality of Life Scale), and substance abuse (Case Managing Rating Scale for Substance Use) were assessed at base line, 1, and 2 years. K-means cluster analysis was used to identify four patterns of premorbid function (stable-good, stable-intermediate, poor-deteriorating, and deteriorating). Gender differences were analysed using χ2 tests. Differences in diagnoses were analysed by one way ANOVA. …

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