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Pharmacotherapy and cognitive behavioural therapy: similarly cost effective compared with community referral for disadvantaged women with major depression

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 Q What is the relative cost effectiveness of pharmacotherapy, cognitive behavioural therapy, and community referral for low income minority women with major depression?

METHODS

Embedded ImageDesign:

Randomised controlled trial.

Embedded ImageAllocation:

Not stated.

Embedded ImageBlinding:

Not stated.

Embedded ImageFollow up period:

Twelve months.

Embedded ImageSetting:

Family planning clinics and paediatric related services in four US counties.

Embedded ImagePatients:

267 low income minority women with major depression on Composite International Diagnostic Interview. Exclusions: bereavement; substance abuse; pregnancy; breastfeeding, or currently receiving mental health care.

Embedded ImageIntervention:

Pharmacotherapy (paroxetine hydrochloride or bupropion hydrochloride for up to six months); cognitive behaviour therapy (CBT; weekly for 8–16 weeks), or community referral (education about depression and management by community services).

Embedded ImageOutcomes:

Intervention and health care costs, depression-free days (days on which …

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