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Evid Based Mental Health 6:42 doi:10.1136/ebmh.6.2.42
  • Therapeutics

Once-daily atomoxetine may reduce attention deficit hyperactivity disorder symptoms in children and adolescents

Adverse effects in children and adolescents with ADHD receiving 6 weeks of daily atomoxetine or placebo

Atomoxetine % (n=85) Placebo % (n=85) Number needed to treat with atomoxetine to harm 1 person (95% CI) Absolute risk increase % (95% CI)
Decreased appetite 20.0 5.9 7 (4 to 24) 14.1 (4.2 to 24.0)
Vomiting 15.3 1.2 7 (5 to 16) 14.1 (6.1 to 22.1)
Nausea 11.8 2.4 11 (6 to 55) 9.4 (1.8 to 17.0)
Asthenia 10.6 1.2 11 (6 to 41) 9.4 (2.5 to 16.3)
Dyspepsia 9.4 0.0 11 (6 to 31) 9.4 (3.2 to 15.6)

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