Progesterone or progestogens v placebo for premenstrual symptoms*
| Outcomes | Treatment | Route of administration | Standardised mean difference (95% CI) |
|---|---|---|---|
| SymptomReduction | Progesterone | All | -0.03 (-0.04 to -0.02) |
| Suppositories | -0.04 (0.03 to 0.05) | ||
| Oral | -0.15 (-0.17 to -0.12) | ||
| Progestogens | All | -0.04 (-0.06 to -0.01) |
| Odds ratio (CI) | |||
|---|---|---|---|
| *Negative standardised mean differences indicate a benefit for treatment. | |||
| †Difference favours placebo group and is not statistically significant. | |||
| Withdrawals resulting from side effects | Progesterone | All | 1.7 (0.4 to 6.8)† |
| Progestogens | All | 1.7 (0.9 to 3.2)† | |









