Methylphenidate v placebo in children and adolescents with attention deficit disorder*
| Outcomes | Standardised mean difference (95% CI) |
|---|---|
| Hyperactivity index (teacher reported) | 0.78 (0.64 to 0.91) |
| Hyperactivity index (parent reported) | 0.54 (0.40 to 0.67) |
| Parent/self reported adverse events | Methylphenidate | Placebo | NNH (CI) |
|---|---|---|---|
| *Abbreviations defined in glossary; NNH and CI calculated from absolute risk difference data in article. | |||
| Decreased appetite | 45% | 14% | 4 (3 to 6) |
| Insomnia | 48% | 31% | 6 (4 to 13) |
| Headache | 18% | 13% | 17 (10 to 72) |
| Stomachache | 24% | 15% | 12 (6 to 84) |
