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We are pleased to respond to Drs Lee and Hoge's1 commentary on our randomised controlled trial (RCT) published in JAMA (a summary of the original article can be found at https://www.ncbi.nlm.nih.gov/pubmed/26241597).2 While we readily acknowledge several limitations to the study, Drs Lee and Hoge have failed to consider or acknowledge several aspects of the study and its results.
The main concern with Lee and Hoge's critique is its focus on a single time-point of data that seems to invite readers to ignore all other data. Lee and Hoge argue that the lack of a statistically significant difference between groups at post-treatment equates, of necessity, to a lack of evidence of effectiveness. The authors neglect to consider that despite appropriate randomisation procedures, which they commend, there were significant differences between groups on baseline PTSD symptoms. Participants in the mindfulness-based stress reduction group had significantly greater severity of baseline PTSD symptoms than those in the present-centred therapy group as measured …
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