rss
Evid Based Mental Health 2:118 doi:10.1136/ebmh.2.4.118
  • Therapeutics

Clozapine improved psychosis without worsening parkinsonism

Clozapine v placebo for decrease in measures of psychosis and parkinsonism at 4 weeks

Psychosis scales Difference in mean decrease (95% CI)*
*CI calculated from data in article. A positive score indicates that the clozapine group improved more than placebo.
†Not significant.
Clinical Global Impression Scale 1.1 (0.4 to 1.8)
Brief Psychiatric Rating Scale 6.7 (2.7 to 10.7)
Modified Brief Psychiatric Rating Scale 6.1 (2.6 to 9.7)
Scale for the Assessment of Positive Symptoms 8.0 (2.5 to 13.5)
Parkinsonism scales
Unified Parkinson's Disease Rating Scale, total score 2.6 (−4.0 to 9.2)†
Unified Parkinson's Disease Rating Scale, tremor score 1.3 (0.1 to 2.6)

This Article

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.