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Evid Based Mental Health 2:95 doi:10.1136/ebmh.2.3.95
  • Aetiology

Review: psychotropic drugs increase the risk of falls in older people

Weighted odds ratio (OR) for the association between various psychotropic drug classes v placebo and ≥1 fall in older people

Drug class Number of studies Number of cohort studies Weighted OR (95% CI)
TCAs = tricyclic antidepressants
Any psychotropic drug 19 11 1.7 (1.5 to 2.0)
Antidepressants 27 11 1.7 (1.4 to 2.0)
Neuroleptics 22 10 1.5 (1.3 to 1.8)
TCAs 12 6 1.5 (1.1 to 2.0)
Sedative/hypnotics 22 9 1.5 (1.4 to 1.7)
Benzodiazepines 13 8 1.5 (1.2 to 1.8)

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