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Evid Based Mental Health 2:74 doi:10.1136/ebmh.2.3.74
  • Therapeutics

Bupropion alone or with a nicotine patch increased smoking cessation rates

Comparison of smoking cessation regimens for point prevalence or continuous abstinence at 1 year*

Abstinence Regimen Intervention Placebo RBI (95% CI) NNT (CI)
*Abbreviations defined in glossary; RBI, NNT, and CI calculated from data in article and from data provided by the author. †Combination regimen=bupropion plus a nicotine patch.
Point prevalence Bupropion 30% 16% 94% (31 to 193) 7 (4 to 16)
Combination† 36% 16% 127% (54 to 240) 5 (4 to 9)
Continuous Bupropion 18% 6% 228% (69 to 548) 8 (5 to 15)
Combination† 22% 6% 229% (108 to 681) 6 (4 to 10)

This Article

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