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ABSTRACT FROM: Xiang AH, Wang X, Martinez MP, et al. Association of maternal diabetes with autism in offspring. JAMA 2015;313:1425–34.
What is already known on this topic
Maternal gestational diabetes has been identified in several prior studies as being associated with elevated risk for autism spectrum disorder in offspring.1–4 Maternal gestational diabetes has also been previously associated with impaired language development in offspring.5 Maternal obesity, another indicator of the metabolic syndrome, has been associated with offspring autism in a prior study.3 No studies have examined the timing of the onset of maternal gestational diabetes with respect to autism risk in offspring.
Methods of the study
This retrospective cohort study used medical record and birth certificate data from a racially and ethnically diverse health maintenance organisation to examine the association of pre-existing maternal type 2 diabetes and maternal gestational diabetes with …
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