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ABSTRACT FROM: Fazel S, Zetterqvist J, Larsson H, et al. Antipsychotics, mood stabilisers, and risk of violent crime. Lancet 2014;384:1206–14.
What is already known on this topic
The benefits of antipsychotics and mood stabilisers in the treatment of not only schizophrenia1 and bipolar disorder,2 but also major depression3 and borderline personality disorder,4 have been established with regard to relapse prevention and readmission rates. Knowledge about other important outcomes of pharmacotherapy is incomplete, specifically when it comes to violent behaviour which has emerged as a recurrent problem linked to periods with severe mental illness.5
Methods of study
In this population-based study (2006–2009), linked Swedish national registers were used to identify 82 647 patients (40 937 men and 41 710 women) who were prescribed antipsychotics or mood stabilisers, their psychiatric diagnoses and subsequent convictions for violent crime (2657 men (6.5%) and 604 women (1.4%)). Each patient was used as their own control by doing within-individual analyses comparing the …
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