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History of depression and previous suicide attempt predict increased risk of suicide attempt following diagnosis of first-episode psychosis

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Question: What is the prevalence of suicide attempts, and what are the predictors of suicide attempts, in children and adolescents with first-episode psychosis?

Population: A total of 110 children and adolescents (aged 9–17 years) participated in the Child and Adolescent First-Episode Psychosis Study (CAFEPS). Inclusions: first-episode psychosis as defined by positive psychotic symptoms (eg, delusions or hallucinations, scoring >4 on items P1 or P3 of the Positive and Negative Syndrome Scale (PANSS)) for less than 6 months.

Setting: Six child and adolescent psychiatry departments, Spain; March 2003 to November 2005.

Prognostic factors: Suicidal behaviour (assessed using the Clinical Global Impression for Severity of Suicidality (CGI-SS) five-point scale, and item 3 of the Hamilton Depression Rating Scale (HDRS)); socioeconomic factors (Hollingshead-Redlich Scale); family history of psychiatric disorders; completed suicide of first-degree and second-degree relatives; psychotic symptoms (PANSS); manic symptoms (Young Mania Rating Scale); depressive symptoms (HDRS); past or current Axis 1 diagnoses, including substance use (Schedule for Affective Disorders and …

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