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Does generalised anxiety disorder (GAD) affect cardiovascular events associated with coronary heart disease (CHD)?
1015 patients with stable coronary heart. Eligible patients had at least one of the following: history of myocardial infarction (MI), 50% stenosis in one or more coronary vessels (angiographic evidence), history of coronary revascularization, diagnosis of CHD or previous evidence of exercise-induced ischaemia (treadmill or nuclear testing).
Medical centres and public health clinics in San Francisco, USA; September 2000 to December 2002.
GAD according to Diagnostic Interview Schedule for DSM-IV criteria.
Cardiovascular events occurring between baseline and March 2009. Events included stroke, heart failure, MI, transient ischaemic attack or death. Heart failure was defined as hospitalisation for a clinical syndrome involving at least two of the following: orthopnoea, third heart sound, pulmonary rales, paroxysmal nocturnal dyspnoea, elevated jugular venous pressure, cardiomegaly or pulmonary oedema on chest radiography. Non-fatal MI was defined based on the presence of symptoms, electrocardiographic changes and cardiac enzymes using standard criteria.
Prospective cohort study. …
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