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Interpersonal therapy or guided self-help CBT improve remission from binge eating compared to a behavioural weight-loss programme at 2-year post-treatment

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Question

Question:

Is interpersonal therapy more effective than either behavioural weight-loss treatment (BWL) or guided self-help based on cognitive behavioural therapy (CBT) in patients with binge-eating disorder (BED), and is this influenced by negative affect?

Patients:

Two hundred and five women and men who were overweight or obese (body mass index 27–45) who met DSM-IV criteria for BED. Main exclusions are as follows: current psychosis or suicidality, bipolar disorder, alcohol or drug dependence in the past 6 months, taking medication or having medical disorders that would affect weight, already in weight-control programme and pregnancy. Randomisation was stratified by negative affect (low or high, Beck Depression Index score cut-off 18 points).

Setting:

Two university outpatient clinics, USA; time period not stated.

Intervention:

Interpersonal therapy (IPT) or BWL or guided self-help based on CBTgsh for 6 months. IPT consisted of 20 sessions and were manualised. The first session was 2 h long, and all other sessions were 50–60 min long. BWL involved moderate calorie restriction and exercise with a target weight loss …

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