Article Text

PDF
Review: depression is associated with increased cancer mortality

Statistics from Altmetric.com

Question

Question:

Are there associations between depression and mortality of cancer patients and do these vary dependent on the study characteristics?

Outcomes:

RR ratio for depression and cancer mortality.

Methods

Design:

Systematic review and meta analysis.

Data sources:

Medline, Cochrane Data Base, PsychLit, and PSYNDEX were searched for relevant studies.

Study selection and analysis:

Criteria for inclusion in the meta analysis were studies including cancer patients or prospective community-based studies reporting cancer mortality; depressive disorders diagnosed according to ICD-10 DSM-III, III-R or IV; or depressive symptoms assessed with self-rating scales or interviewer ratings. Also, statistics could be calculated or estimated for associations between depression and mortality. RR were calculated for each study and pooled using random-effects models. Heterogeneity was assessed using the Q statistic. Analyses were carried out to look at the effects of potential moderator variables.

Main results

A total of 76 studies met inclusion criteria (176 863 …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles