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The articles we select for Evidence-Based Mental Health must pass two stages: first they must pass our basic validity criteria and then the editors assess each article for clinical relevance. A number of articles meet the inclusion criteria but are not abstracted due to lack of space. We will highlight the most interesting of these here and list the rest.

Both Kraepelin and Bleuler noted that early signs of schizophrenia could be observed in childhood, many years before the onset of clinical symptoms. However, it took another century for the neurode-velopmental hypothesis of schizophrenia to challenge the belief that it was a disorder of adult onset. Since then successive studies have provided reliable evidence of abnormalities in interpersonal relationships, attentional deficits and neurodevel-opmental immaturities in children who later develop schizophrenia. This analysis (

) from the Avon Longitudinal Study of Parents and …

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