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Incidence of schizophrenia lower in people with type I diabetes

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Hannu Juvonen

Correspondence to: Hannu Juvonen, MD, Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland; hannu.juvonen@ktl.fi

QUESTION

Question:

What is the incidence of schizophrenia in people with type 1 diabetes in Finland?

Population:

All individuals born 1950–9 in Finland (896 175 people) identified through the National Population Register. Of these, 5009 were found to have type 1 diabetes based on the Social Insurance Institution of Finland register.

Setting:

General population, Finland; followed up from 1969–91.

Assessment:

Diagnoses of type 1 diabetes and of schizophrenia (ICD-8 or DSM-III-R) during follow-up were identified through the Social Insurance Institution of Finland register, the National Hospital Discharge Register, and the Pension Register. A broad concept of schizophrenia was used, which included schizoaffective, schizophreniform, and schizotypal personality disorders. To control for reduced sensitivity in the registers, the rate of false positives was assessed in a subsample of 906 individuals in whom DSM-IV diagnoses were made independently by two psychiatrists based on available case note information from hospitals and mental health institutions. All schizophrenia …

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