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Metabolic syndrome common in people with psychotic disorders, particularly in users of high potency antipsychotics

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Jaana Suivisaari

Correspondence to: Jaana Suivisaari, Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FIN-00300 Helsinki, Finland; jaana.suvisaari@ktl.fi

QUESTION

Question:

What is the prevalence of metabolic syndrome in people with psychotic disorders or using antipsychotic medications?

Population:

Subset of 5434 people (aged over 30 years) enrolled in the Health 2000 Study who had available measurements relating to metabolic syndrome that were taken after fasting for 4 hours.

Setting:

Primary care settings across 80 municipalities in Finland; recruitment September 2000 to June 2001.

Assessment:

People who were screened positive for a possible psychotic disorder (reported a diagnosis, showed signs of psychotic or manic symptoms during health examination) were interviewed using the research version of the Structured Clinical Interview for DSM-IV-TR to diagnose psychotic disorders. Diagnoses were classified as schizophrenia, other non-affective psychotic disorders (including schizophreniform and schizoaffective disorder), and affective psychosis (bipolar I disorder and major depressive disorder with psychotic symptoms). Diagnosis of metabolic syndrome was made if people fulfilled ⩾3 NECP ATP-III criteria: fasting triglycerides ⩾150 mg/dl; waist circumference >88 cm in women or >102 cm in …

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