Article Text

PDF
Review: Adding Chinese herbal medicine to antipsychotics may improve some outcomes in schizophrenia, but more high quality trials are needed

Statistics from Altmetric.com

John Rathbone

Cochrane Schizophrenia Group, Academic Department of Psychiatry and Behavioural Sciences, University of Leeds, 15 Hyde Terrace, Leeds LS2 9LT, UK; jrathbone@cochrane-sz.org

QUESTION

Question:

Is Chinese herbal medicine an effective treatment for schizophrenia?

Outcomes:

Global state (Clinical Global Impression scale), mental state (Brief Psychiatric Rating Scale, Scale for Assessment of Negative Symptoms), leaving the study early, adverse effects.

METHODS

Design:

Systematic review and meta-analysis.

Data sources:

Cochrane Schizophrenia Group’s trial register, including searches of MEDLINE, CINAHL, BIOSIS Inside, EMBASE, CENTRAL and PsycINFO; Chinese Medical Literature Analysis and Retrieval System, China National Knowledge Infrastructure Database, Chinese Biomedical Database, and the Allied Complementary Medicine Database were searched in 2003. Hand searches of journals and conference proceedings were also carried out.

Study selection and analysis:

Randomised controlled trials (RCTs) in people with schizophrenia or related psychosis (any diagnostic criteria), using any Chinese herbal medicine in comparison with any other therapy. Trials were excluded if there was >50% loss to follow-up. Weighted mean differences for continuous data and relative risks for binary outcomes were calculated used fixed …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.