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Review: Slow repetitive transcranial magnetic stimulation reduces auditory hallucinations in people with schizophrenia

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Does slow repetitive transcranial magnetic stimulation reduce auditory hallucinations in people with schizophrenia?

Aleman A, Sommer IE, Kahn RS. Efficacy of slow repetitive transcranial magnetic stimulation in the treatment of resistant auditory hallucinations in schizophrenia: a meta-analysis. J Clin Psychiatry 2007;68:416–21.

METHODS

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Systematic review with meta-analysis.

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PubMed and Web of Science; search date February 2006.

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Parallel or crossover randomised controlled trials (RCTs) of slow repetitive transcranial magnetic stimulation (rTMS) versus sham control in people with schizophrenia that used appropriate rating scales for auditory hallucination. As hallucinations were measured pre- and post-treatment and not all studies used the same hallucination rating scale, standardised mean gain effect sizes were calculated. In the meta-analysis, effect sizes were weighted according to sample size. Heterogeneity was assessed using Q statistic. Sensitivity analyses were performed if there …

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