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Q Is brief cognitive-behavioural therapy effective for people with schizophrenia?
Randomised controlled trial.
Single blind (assessors blinded).
Six healthcare sites, UK; time period not stated.
422 people with schizophrenia (ICD-10). Most participants had ongoing symptoms or were at risk of relapse. Exclusions: currently experiencing schizophrenia relapse, primary diagnosis of alcohol or substance abuse, organic brain disease, or learning disability.
Brief cognitive-behavioural therapy (CBT: 6 technique-based sessions over 2–3 months given by trained mental health nurses—including techniques for managing positive and negative symptoms and improving medication compliance) or usual care.
Primary outcomes: overall symptoms (Comprehensive Psychopathological Rating Scale (CPRS)); insight (Insight Rating Scale (IRS)); depression (Montgomery-Asberg Depression Rating Scale (MADRS)). Secondary outcomes: positive symptoms (Psychotic Symptom Rating Scales (PSYRATS)); negative symptoms …
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