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Q What is the efficacy of group cognitive behavioural therapy compared with sertraline for reducing obsessive-compulsive disorder symptoms in adults?
Randomised controlled trial.
Single blind (assessors blinded).
Follow up period:
Twelve weeks (treatment period only).
Outpatient setting in Brazil; March 2002 to December 2003.
Fifty six adults (mean 38.5 years) with diagnosed with DSM-IV obsessive-compulsive disorder (OCD; Mini-International Neuropsychiatric Interview – Brazilian version), and a Yale-Brown Obsessive Compulsive Scale (YBOCS) score of ⩾16. Main exclusion criteria: moderate to severe major depression, Beck Depression Inventory score >16, bipolar disorder, severe personality disorder, psychotic disorder, substance related disorder in the previous six months, Tourette’s syndrome, or organic brain disease.
Group cognitive behavioural therapy (CBT; weekly two-hour group session) or sertraline (50 mg/day in the first week and 100 mg/day subsequently) for 12 weeks. Group CBT was provided by a therapist with at least 10 years’ experience in CBT, and included …
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