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Evid Based Mental Health 1:46 doi:10.1136/ebmh.1.2.46
  • Therapeutics

Buprenorphine and methadone were equally effective in reducing opiate or cocaine use

Use of opioids and cocaine during maintenance treatment

Outcome at 24 weeks Methadone 65 mg Buprenorphine 12 mg Methadone 20 mg Buprenorphine 4 mg
Mean rate of opioid positive tests 45% 58% 72% 77%
≥3 weeks opioid abstinence 61% 41% 23% 14%
≥3 weeks cocaine abstinence 50% 35% 40% 21%

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