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Evidence-Based Mental Health 2004;7:98-99; doi:10.1136/ebmh.7.4.98
Copyright © 2004 by BMJ Publishing Group Ltd, Royal College of Psychiatrists, & British Psychological Society.
Evidence-Based Mental Health 2004; 7:98-99
© 2004 BMJ Publishing Group Ltd., Royal College of Psychiatrists, & British Psychological Society

Editorial

The worm turns: publication bias and trial registers revisited

John Geddes, MD, Peter Szatmari, MD, David Streiner, PhD

Editors, EBMH

Key Words: publication bias • trial registers • paroxetine

The first 150 words of the full text of this article appear below.

Readers of Evidence-Based Mental Health will be familiar with the fundamental rationale for systematic reviews: reviews should have adequate and well described methods and, in particular, avoid the biased selection of primary studies dependent on their results. A comprehensive and reproducible literature search is now recognised to be a key feature of systematic reviews. We know a lot about the advantages and limitations of electronic bibliographic databases, such as Medline.1 There is now a substantial body of empirical evidence about the various kinds of bias that can plague the identification and selection of studies for reviews, including publication bias (studies with significant results are more likely to get published than studies without significant results), English language bias (studies with significant results more likely to be published in English language journals), citation bias (studies with significant results more likely to be cited) and so on.2 As long as studies get published . . . [Full text of this article]


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