© 2004 BMJ Publishing Group Ltd., Royal College of Psychiatrists, & British Psychological Society
Prognosis
Psychological function is mildly impaired for prolonged periods before and after first unipolar major depressive episode
Ormel J, Oldehinkel AJ, Nolen WA, et al. Psychosocial disability before, during, and after a major depressive episode; A 3-wave population-based study of state, scar, and trait effects. Arch Gen Psychiatry 2004;61:38792.
Q Is psychosocial disability present before and after a persons first unipolar major depressive episode?
| The first 150 words of the full text of this article appear below. |
Design:
Prospective longitudinal study.
Setting:
General population, the Netherlands; enrolment 199699.
Population:
4796 people aged 1864 years in 1996, randomly sampled from the general population. People with bipolar disorders were excluded.
Prognostic factors:
Psychiatric data were obtained by Composite International Diagnostic Interview, as part of the Netherlands Mental Health Survey and Incidence Study (NEMSIS). Psychosocial function was assessed using the employment, partner, housekeeping, and leisure scales of the Groningen Social Disability Schedule. Between subject and within subject differences in disability were compared using Students t test. Retest and time effects were tested using ANOVA. Differences were expressed as effect sizes, which were calculated by dividing the mean difference in disability by the standard deviation of disability in the two groups.
Follow up period:
One and three years.
At three years, 216 people had developed and recovered from a first major depressive episode, while 118 people had developed and recovered from
Centre for Mental Health Studies, University of Newcastle, Newcastle,
Australia
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