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Evidence-Based Mental Health 2003;6:14; doi:10.1136/ebmh.6.1.14
Copyright © 2003 by BMJ Publishing Group Ltd, Royal College of Psychiatrists, & British Psychological Society.
Evidence-Based Mental Health 2003; 6:14
© 2003 BMJ Publishing Group, Royal College of Psychiatrists, & British Psychological Society

Aetiology

Existing psychological problems predict depression in primary care better than sociodemographic factors

Barkow K, Maier W, Ustun TB et al. Risk factors for new depressive episodes in primary health care: an international prospective 12-month follow-up study. Psychological Medicine 2002 May; 32: 595–608.[Medline]

QUESTION: What are the risk factors for depressive episodes in primary care?

Key Words: risk factors

The first 150 words of the full text of this article appear below.

Design

Population-based cohort study with 1 year of follow up. Outcome assessors were blinded to baseline assessments.

Setting

15 primary care centres in 14 countries in Africa, Asia, Europe, North America and South America.

Participants

Stratified sample of 2445 people without initial depression in the World Health Organisation ‘Psychological Problems in General Health Care’ study who attended a participating primary care clinic. All were younger than 66 years (mean age 41 years); 63% women.

Assessment of risk factors

Sociodemographic variables (age, gender, martial status, years of formal education, employment, location); psychological and psychiatric problems, and social disability measured using questionnaires at baseline.

Main outcome measures

Presence of a depressive episode at 12-month follow up measured using ICD-10 criteria. Logistic regression assessed the link between depressive episodes and risk factors.

Main results

After 12 months, 4.4% of participants had a new depressive episode. Factors related to the development of newdepressive episodes included repeated suicidal thoughts, previous depressive episodes, identification as a psychiatric case . . . [Full text of this article]

Daniel O'Connor, MD, FRANZCP

Professor of Psychiatry of Old Age
Monash University
Melbourne, Australia


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