© 2000 Evidence-Based Mental Health
Individual drug counselling plus group drug counselling was effective in patients with cocaine dependence
Crits-Christoph P, Siqueland L, Blaine J, et al. Psychosocial treatments for cocaine dependence: National Institute on Drug Abuse Collaborative Cocaine Treatment Study. Arch Gen Psychiatry 1999 Jun;56:493–502.
QUESTION: In patients with cocaine dependence, how effective are psychosocial treatments?
Randomised (allocation concealed*), blinded {outcome assessors}*
, controlled trial with 12 months of follow up.
5 university and hospital sites in the US.
487 patients between 18 and 60 years of age (mean age 34 y, 77% men) with a principal diagnosis of DSM-IV cocaine dependence and who had used cocaine in the previous 30 days. Exclusion criteria included unstable living arrangements, opioid or polysubstance dependence, dementia, psychotic symptoms, unstable medical illness, and suicide or homicide risk. 83% of patients completed the 9 or 12 month follow up assessment.
Patients were allocated to 1 of 4 manual guided treatments: (1) individual drug counselling plus group drug counselling (IDC + GDC) (n=121); (2) cognitive therapy plus GDC (CT + GDC) (n=119); (3) supportive expressive therapy plus GDC (SE + GDC) (n=124); or (4) GDC alone (n=123). Treatment lasted for 6 months.
Primary outcome measures were change in the Addiction Severity
Louisiana State University Medical Center Shreveport, Louisiana, USA
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