OTHER
Therapeutics
Review: limited evidence to support pharmacological therapy for amphetamine withdrawal
| The first 150 words of the full text of this article appear below. |
Is pharmacological therapy, alone or in combination with psychosocial treatment, effective for amphetamine withdrawal?
Discontinuation rates, average global state score (eg, Clinical Global Impression), average score on withdrawal symptomatology assessments (eg, Amphetamine Withdrawal Questionnaire), average score in craving rating scales (eg, Questionnaire for Evaluating Cocaine Craving and Related Responses) and patient satisfaction (measured by type and number of adverse events).
Systematic review with meta-analysis.
The Cochrane Central Register of Controlled Trials, MEDLINE, PsycINFO and CINAHL (searched from inception to 1 May 2008). Reference lists of identified studies and conference proceedings were hand searched.
Two independent reviewers appraised the studies and selected randomised controlled trials comparing any kind of pharmacological treatment, alone or in combination with a psychosocial treatment, placebo or any psychosocial treatment for amphetamine withdrawal. Studies of other drugs in addition to amphetamine were included provided >50% of participants were withdrawing from amphetamine and there was separate reporting
National Addiction Centre, Kings College London, UK
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