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Evidence-Based Mental Health 2009;12:52; doi:10.1136/ebmh.12.2.52
Copyright © 2009 by BMJ Publishing Group Ltd, Royal College of Psychiatrists, & British Psychological Society.

THERAPEUTICS

Review: non-pharmacological interventions reduce antipsychotic induced weight gain

The first 150 words of the full text of this article appear below.

QUESTION

Question:

Are non-pharmacological interventions effective in controlling antipsychotic induced weight gain in people with schizophrenia spectrum disorders?

Outcomes:

Primary: change in body weight; change in body mass index (BMI) post-treatment; secondary: body weight and BMI at follow-up.

METHODS

Design: Systematic review with meta-analysis.

Data sources: The following databases were searched in May 2007: Cochrane Central Register of Controlled Trials, Medline, EMBASE, PsycINFO, CINAHL, UMI Proquest Digital Dissertations, Information Science Citation Index Expanded Information Social Sciences Citation Index, Information Arts and Humanities Citation Index, registers of ongoing clinical trials, ISI Science and Technology proceedings and ISI Information Social Science and Humanities proceedings. Hand searching of reference lists and key journals (from January 2000 to May 2007) was used to identify additional articles.

Study selection and analysis: The review included randomised controlled trials (RCTs) comparing the efficacy of non-pharmacological interventions to care as usual or an active comparator in preventing or reducing weight gain associated . . . [Full text of this article]

Roger S McIntyre

Associate Professor of Psychiatry and Pharmacology, University of Toronto, Toronto, Canada


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