PROGNOSIS
Developing depression after a myocardial infarction increases risk of cardiac mortality but pre-existing depression does not
| The first 150 words of the full text of this article appear below. |
Does the association between depression and cardiac mortality differ between people with pre- and post-myocardial infarction depression?
588 adults (mean age 60.0 (SD 11.1) years; 70% male) admitted to hospital with suspected myocardial infarction (MI) who were found to meet WHO criteria for MI plus two of the following on screening: characteristic ECG changes, history of typical chest pain or serial increase in creatine phosphokinase (CPK) to twice or more the normal limits. Exclusion criteria were: serious comorbidities, too unwell to complete assessment, aged 80 years or older, limited spoken English or lived outside the catchment area.
Four inner city hospitals, UK; screening October 1997–November 1999.
The main factor of interest was depression and its time of onset, either pre-MI or post-MI. At baseline, participants completed the Hospital Anxiety and Depression Scale (HADS) on their mental state in the week before the MI and then again at 12 months after
Centre of Research on Psychology in Somatic Diseases, Department of Medical Psychology, Tilburg University, Tilburg, The Netherlands
Centre of Research on Psychology in Somatic Diseases, Department of Medical Psychology, Tilburg University and Department of Psychiatry, University of Groningen, Tilburg, Groningen, The Netherlands
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