THERAPEUTICS
Escitalopram and problem solving therapy reduce the incidence of post-stroke depression
| The first 150 words of the full text of this article appear below. |
Can escitalopram or problem solving therapy prevent post-stroke depression?
176 non-depressed participants within 3 months of haemorrhagic or ischaemic stroke. Exclusions were DSM-IV based major or minor depression (research criteria); >11 on the Hamilton-17 Depression Rating Scale; severe neuropsychological deficits; other life threatening medical conditions; neurodegenerative disorders; and DSM-IV alcohol or substance abuse or dependence within the past 12 months.
Two university hospitals, USA; enrolment 2003–2007.
One of three 2 month regimens: escitalopram (10 mg/day if <65 years old, 5 mg/day if 
65 years old; taken in the morning), placebo pill or problem solving therapy (PST) (six sessions over the first 12 weeks and six reinforcement sessions up to 12 months). PST was delivered by therapists who had completed training in the manual based intervention and all sessions were videotaped and assessed for adherence.
Major or minor depression (defined as meeting DSM-IV criteria for either of these diagnoses, as assessed
Fondazione Santa Lucia-IRCCS, Rome, Italy
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
