PROGNOSIS
Mortality in people with dementia taking antipsychotics higher than in those taking other psychiatric medications
| The first 150 words of the full text of this article appear below. |
Dr Helen C Kales
Correspondence to: Dr Helen C Kales, MD, Department of Psychiatry, University of Michigan, Box 5765, 4250 Plymouth Road, Ann Arbor, MI 48109, USA; kales@umich.edu
Is there a difference in mortality rate in the year after starting a new antipsychotic for neuropsychiatric symptoms of dementia and other psychiatric drugs?
10 615 older adults (over 65 years old) diagnosed with dementia in fiscal years 2002 or 2003 who started outpatient psychiatric medication within 6 months of being diagnosed with dementia. Exclusions: using psychiatric medication in 6 months prior to dementia diagnosis; receiving lithium; having a seizure disorder.
National Department of Veterans Affairs (VA) data registries, USA; fiscal years 2001–5.
Type of psychiatric medication: antipsychotic (conventional, atypical, or both) or other. Analyses were adjusted for potential confounders, including: age, gender, use of cholinesterase inhibitors, delirium diagnosis present at time of first prescription filling, date of starting psychiatric medication, schizophrenia
St Charles Hospital, Central North West London Foundation NHS Trust, London, UK
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