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Depressed inpatients: treatment with psychotherapy plus pharmacotherapy superior to standard treatment

Dr Schramm

Correspondence to: Dr Schramm, University Medical Center Freiburg, Department of Psychiatry and Psychotherapy, Hauptstrasse 5, 79104 Freiburg, Germany; Elisabeth.Schramm@uniklinik-freiburg.de

QUESTION
Question:
Is psychotherapy better than usual clinical management for inpatients with depression who are also being treated with pharmacotherapy?

Patients:
130 people aged 18–65 years old with DSM-IV major depressive disorder referred for psychiatric hospitalisation, who had a score of 16 on the 17-item Hamilton Depression Rating Scale (HAM-D). Exclusion criteria: bipolar I disorder, substance abuse or dependency, other primary axis I disorders, organic mental disorder, psychotic symptoms, severe cognitive impairment, active suicide ideation.

Setting:
Acute psychiatric hospital; enrolment November 2000 to August 2003.

Intervention:
Interpersonal psychotherapy (IPT) or clinical management (usual care). IPT had been adapted for an inpatient setting and included 15 individual sessions (each about 50 minutes three times weekly over 5 weeks), 8 IPT group sessions, some of which included significant others in some of the sessions. Clinical management . . . [Full text of this article]

Matthias Schwannauer

University of Edinburgh, Edinburgh, UK